{"product_id":"rcan1-polyclonal-antibody-e-ab-67645","title":"RCAN1 Polyclonal Antibody - E-AB-67645","description":"\u003cp\u003eRCAN1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67645-60, E-AB-67645-120, E-AB-67645-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RCAN1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RCAN1; ADAPT78; CSP1; DSC1; DSCR1; MCIP1; RCN1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P53805\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RCAN1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 13kDa\/19kDa\/22kDa\/28kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 31kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146448928947,"sku":"E-AB-67645-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146448961715,"sku":"E-AB-67645-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146448994483,"sku":"E-AB-67645-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b63c4797-8366-4a27-a1b6-57ed317297f3.png?v=1710295776","url":"https:\/\/afsbio.com\/products\/rcan1-polyclonal-antibody-e-ab-67645","provider":"AFSBio Inc.","version":"1.0","type":"link"}