{"product_id":"rcc1-rabbit-pab-es8532","title":"RCC1 rabbit pAb - ES8532","description":"\u003cp\u003eRCC1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8532-50, ES8532-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: disease:Patients with Raynaud disease produce antibodies that bind to RCC1., function:Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1\/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA., similarity:Contains 7 RCC1 repeats., subcellular location:Becomes dispersed throughout the cytoplasm during mitosis.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: RCC1 CHC1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, IHC-p 1:50-200 ELISA 1:10000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide from human protein at AA range: 301-350\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 45kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 1104\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P18754\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Chromosome. Cytoplasm. Predominantly nuclear in interphase cells (PubMed:12194828). Binds to mitotic chromosomes (PubMed:12194828, PubMed:17435751, PubMed:20668449).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202384257203,"sku":"ES8532-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202384289971,"sku":"ES8532-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_7f3067fc-ba71-479c-94fd-b67f1f2686d8.png?v=1767127993","url":"https:\/\/afsbio.com\/products\/rcc1-rabbit-pab-es8532","provider":"AFSBio Inc.","version":"1.0","type":"link"}