{"product_id":"recombinant-2019-ncov-3c-like-proteinase-protein-his-tag-pksr030465","title":"Recombinant 2019-nCoV 3C-like Proteinase Protein (His Tag) - PKSR030465","description":"\u003cp\u003eRecombinant 2019-nCoV 3C-like Proteinase Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSR030465-10, PKSR030465-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: 3C-likease\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: M Proteinase; 3CL Proteinase\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: SARS-CoV-2\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: YP_009725301.1\u003c\/p\u003e\n\n\u003cp\u003eBackground: The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ser1-Gln306\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μM filtered solution of PBS, 1 mM EDTA, 10% Glycerol, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 36.1 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 33 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43149093601459,"sku":"PKSR030465-10","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43149093634227,"sku":"PKSR030465-50","price":700.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_f6682f89-1a7e-44eb-b28d-245f8e9bdd45.png?v=1710340555","url":"https:\/\/afsbio.com\/products\/recombinant-2019-ncov-3c-like-proteinase-protein-his-tag-pksr030465","provider":"AFSBio Inc.","version":"1.0","type":"link"}