{"product_id":"recombinant-2019-ncov-nsp10-n-6his-ept002","title":"Recombinant 2019-nCoV NSP10 (N-6His) - EPT002","description":"\u003cp\u003eRecombinant 2019-nCoV NSP10 (N-6His)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: EPT002-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: SARS-CoV 2 nsp10; SARS-CoV 2 Growth factor-like peptide; SARS-CoV 2 GFL\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant 2019-nCoV NSP10 is produced by our E.coli expression system and the target gene encoding Ala1-Gln139 is expressed with a 6His tag at the N-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAccession: YP_009725306.1\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 17.9 KDa\u003c\/p\u003e\n\n\u003cp\u003eApparent Molecular Weight: 18 KDa, reducing conditions\u003c\/p\u003e\n\n\u003cp\u003eStorage Condition: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003ePurity: Greater than 80% as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eDelivery Condition: The product is shipped on dry ice\/polar packs. Upon receipt, store it immediately at the temperature listed below.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"Default Title","offer_id":43211010539699,"sku":"EPT002-50","price":1174.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_7950c7d9-c325-4f0b-b307-4dd64320c055.png?v=1767117589","url":"https:\/\/afsbio.com\/products\/recombinant-2019-ncov-nsp10-n-6his-ept002","provider":"AFSBio Inc.","version":"1.0","type":"link"}