{"product_id":"recombinant-aldh1a1-monoclonal-antibody-e-ab-81434","title":"Recombinant ALDH1A1 Monoclonal Antibody - E-AB-81434","description":"\u003cp\u003eRecombinant ALDH1A1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-81434-50, E-AB-81434-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ALDH1A1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ALDH1A1; ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC-P\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Rabbit Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: R09-3B9\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P00352\u003c\/p\u003e\n\n\u003cp\u003eBackground: ALDH1A1(Aldehyde dehydrogenase family 1 member A1 ), also named as ALDC, ALDH1 and PUMB1, belongs to the aldehyde dehydrogenase family. The ALDH1A1 gene encodes a liver cytosolic isoform of acetaldehyde dehydrogenase, an enzyme involved in the major pathway of alcohol metabolism after alcohol dehydrogenase. ALDH1A1 plays a critical role in protection against oxidative stress-induced cytotoxicity in lens epithelial cells. And it is important for multiple biological activities including drug resistance, cell differentiation, and oxidative stress response. As a novel cancer stem cell marker, ALDH1A1 can be used for tumors whose corresponding normal tissues express ALDH1A1 in relatively restricted or limited levels such as breast, lung, ovarian or colon cancer.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 300 μg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human ALDH1A1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000 IHC 1:20-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 55kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 55kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43149025214643,"sku":"E-AB-81434-50","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43149025247411,"sku":"E-AB-81434-100","price":364.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_09b3dc9d-7a3d-47b0-bfba-c9a4da7cfddb.png?v=1710338543","url":"https:\/\/afsbio.com\/products\/recombinant-aldh1a1-monoclonal-antibody-e-ab-81434","provider":"AFSBio Inc.","version":"1.0","type":"link"}