{"product_id":"recombinant-caspase-9-monoclonal-antibody-e-ab-81541","title":"Recombinant Caspase 9 Monoclonal Antibody - E-AB-81541","description":"\u003cp\u003eRecombinant Caspase 9 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-81541-50, E-AB-81541-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Caspase 9\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: APAF-3; APAF3; Apoptosis related cysteine peptidase; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; CASP-9; CASP9; CASP9; Caspase 9 apoptosis related cysteine peptidase; Caspase 9 Dominant Negative; Caspase 9c; Caspase-9; Caspase-9 subunit p10; ICE LAP6; ICE like apoptotic protease 6; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; PPP1R56; protein phosphatase 1; regulatory subunit 56; RNCASP9\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Rabbit Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: R09-4C4\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P55211\u003c\/p\u003e\n\n\u003cp\u003eBackground: Caspase 9, apoptosis-related cysteine protease (CASP9, synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Capase 9 is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 300 μg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human Caspase-9\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 46kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 46kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43149033537715,"sku":"E-AB-81541-50","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43149033570483,"sku":"E-AB-81541-100","price":364.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_fe52b526-5872-4137-8380-9926d52cdc12.png?v=1710338837","url":"https:\/\/afsbio.com\/products\/recombinant-caspase-9-monoclonal-antibody-e-ab-81541","provider":"AFSBio Inc.","version":"1.0","type":"link"}