{"product_id":"recombinant-chiken-igf1-igf-i-igf-1-protein-his-tag-pdeo100008","title":"Recombinant chiken IGF1\/IGF‑I\/IGF-1 protein (His tag) - PDEO100008","description":"\u003cp\u003eRecombinant chiken IGF1\/IGF‑I\/IGF-1 protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDEO100008-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IGF1; IGF-1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Insulin-like growth factor I; IGF1;\u003c\/p\u003e \n\n\u003cp\u003eUNIProt ID: P18254\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Developmental Biology; Neuroscience; signal Transduction; Stem Cells; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Chicken\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P18254\u003c\/p\u003e\n\n\u003cp\u003eBackground: Insulin-like growth factor I (IGF-I or IGF-1), also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. IGF-I regulates glucose and fatty acid metabolism, steroid hormone activity, and cartilage and bone metabolism. It plays an important role in muscle regeneration and tumor progression. IGF-I\/IGF-1 binds IGF-I R, IGF-II R, and the insulin receptor, although its effects are mediated primarily by IGF-I R. The IGF-I protein associates with IGF binding proteins thereby increasing its plasma half-life and modulating its interactions with receptors.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gly 49-Met 153\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 11.44 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 13 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43083597643955,"sku":"PDEO100008-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_44fe799d-921a-4bb2-95e1-e7cedf874225.png?v=1708944977","url":"https:\/\/afsbio.com\/products\/recombinant-chiken-igf1-igf-i-igf-1-protein-his-tag-pdeo100008","provider":"AFSBio Inc.","version":"1.0","type":"link"}