{"product_id":"recombinant-ckbeta8-1-ccl23-human-bk0190","title":"Recombinant Ckbeta8‑1\/CCL23, Human - BK0190","description":"\u003cp\u003eRecombinant Ckbeta8‑1\/CCL23, Human\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0190-10, BK0190-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: CHO\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 10.5 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 98% as analyzed by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: The EC50 value of human Ck beta 8‑1\/CCL23 on Caˆ2+ mobilization assay in CHO-K1\/Ga15\/hCCR1 cells (human Ga15 and human CCR1 stably expressed in CHO-K1 cells) is less than 0.4 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCVRM\u003cbr\u003e\n LKLDTRIKTRKN\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant human Ck beta 8‑1\/CCL23 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human Ck beta 8‑1\/CCL23 should be stable up to 1 week at 4°C or up to 2 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family that is also known as Macrophage inflammatory protein 3 (MIP-3) and Myeloid progenitor inhibitory factor 1 (MPIF-1). CCL23 is predominantly expressed in lung and liver tissue, but is also found in bone marrow and placenta.CCL23 is highly chemotactic for resting T cells and monocytes and slightly chemotactic for neutrophils. It has also been attributed to an inhibitory activity on hematopoietic progenitor cells. CCL23 is a ligand for the chemokine receptor CCR1.Recombinant human Ck beta 8‑1\/CCL23 produced in CHO cells is a single polypeptide chain containing 92 amino acids. A fully biologically active molecule, rhCk beta 8‑1\/CCL23 has a molecular mass of 10.5 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882248081587,"sku":"BK0190-10","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882248114355,"sku":"BK0190-50","price":691.77,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_6abf2caf-e4fa-4e19-85ee-7d42b2c1b88c.jpg?v=1702050038","url":"https:\/\/afsbio.com\/products\/recombinant-ckbeta8-1-ccl23-human-bk0190","provider":"AFSBio Inc.","version":"1.0","type":"link"}