{"product_id":"recombinant-cynomolgus-cd38-adp-ribosyl-cyclase-1-protein-fc-tag-pksq050040","title":"Recombinant Cynomolgus CD38\/ADP-ribosyl Cyclase 1 Protein (Fc Tag) - PKSQ050040","description":"\u003cp\u003eRecombinant Cynomolgus CD38\/ADP-ribosyl Cyclase 1 Protein (Fc Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSQ050040-10, PKSQ050040-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD38; ADP-ribosyl Cyclase 1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase; CD38; T10\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q5VAN0\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Cynomolgus macaques\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q5VAN0\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Leu44-Ile301\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 57 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 65-95 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072226984115,"sku":"PKSQ050040-10","price":456.4,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072227016883,"sku":"PKSQ050040-50","price":1150.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_50df314b-eb97-4235-b868-ba281dad0024.png?v=1708684655","url":"https:\/\/afsbio.com\/products\/recombinant-cynomolgus-cd38-adp-ribosyl-cyclase-1-protein-fc-tag-pksq050040","provider":"AFSBio Inc.","version":"1.0","type":"link"}