{"product_id":"recombinant-cynomolgus-fgl1-c-6his-pksq050095","title":"Recombinant Cynomolgus FGL1 (C-6His) - PKSQ050095","description":"\u003cp\u003eRecombinant Cynomolgus FGL1 (C-6His)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSQ050095-10, PKSQ050095-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: FGL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Angiopoietin-related protein 4; 425O18-1; Angiopoietin-like protein 4; Fasting-induced adipose factor; Hepatic fibrinogen\/angiopoietin-related protein; HFARP; Secreted protein Bk89; Angptl4; Farp; Fiaf; Ng27\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Cynomolgus macaques\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: BLI\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: A0A2K5X990\u003c\/p\u003e\n\n\u003cp\u003eAccession: A0A2K5X990\u003c\/p\u003e\n\n\u003cp\u003eBackground: Hepassocin, also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1), is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .\u003c\/p\u003e\n\n\u003cp\u003eActivity: Loaded Cynomolgus LAG-3-Fc(Cat#PKSQ050015) on Protein A Biosensor, can bind Cynomolgus FGL1-His(Cat#PKSQ050095) with an affinity constant of 28.6nM as determined in BLI assay.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Leu23-Ile312\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Trehalose, 300mM NaCl, 50% Glycerol, 0.05% Tween 80, pH 8.5\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 34.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43118130823347,"sku":"PKSQ050095-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43118130856115,"sku":"PKSQ050095-50","price":623.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9698de2b-67d9-403e-8cd4-e1f343c3f23c.png?v=1709636780","url":"https:\/\/afsbio.com\/products\/recombinant-cynomolgus-fgl1-c-6his-pksq050095","provider":"AFSBio Inc.","version":"1.0","type":"link"}