{"product_id":"recombinant-cynomolgus-macaques-abl1-protein-his-tag-pdec100003","title":"Recombinant Cynomolgus macaques ABL1 protein (His tag) - PDEC100003","description":"\u003cp\u003eRecombinant Cynomolgus macaques ABL1 protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDEC100003-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ABL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Abelson tyrosine protein kinase 1; ABL 1; bcr\/abl; JTK7; p150; Proto-oncogene c-Abl; v abl\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: A0A2K5X6F2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cancer; Epigenetics and Nuclear Signaling; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Cynomolgus macaques\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: A0A2K5X6F2\u003c\/p\u003e\n\n\u003cp\u003eBackground: Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Phe 264\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28.93 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43072296321203,"sku":"PDEC100003-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8f507bb5-4df1-469d-9173-d80ea74d3ed5.png?v=1708685323","url":"https:\/\/afsbio.com\/products\/recombinant-cynomolgus-macaques-abl1-protein-his-tag-pdec100003","provider":"AFSBio Inc.","version":"1.0","type":"link"}