{"product_id":"recombinant-cynomolgus-pd-l2-b7-dc-cd273-protein-fc-tag-pksq050032","title":"Recombinant Cynomolgus PD-L2\/B7-DC\/CD273 Protein (Fc Tag) - PKSQ050032","description":"\u003cp\u003eRecombinant Cynomolgus PD-L2\/B7-DC\/CD273 Protein (Fc Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSQ050032-10, PKSQ050032-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PD-L2; B7-DC; CD273\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Programmed Cell Death 1 Ligand 2; PD-1 Ligand 2; PD-L2; PDCD1 Ligand 2; Programmed Death Ligand 2; Butyrophilin B7-DC; B7-DC; CD273; PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: A4GW30\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Cynomolgus macaques\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eAccession: A4GW30\u003c\/p\u003e\n\n\u003cp\u003eBackground: Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN\/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Leu20-Pro219\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 49.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60-90 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072226492595,"sku":"PKSQ050032-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072226525363,"sku":"PKSQ050032-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_82a01a23-ff11-47cb-b48d-f14bd6f06fe5.png?v=1708684643","url":"https:\/\/afsbio.com\/products\/recombinant-cynomolgus-pd-l2-b7-dc-cd273-protein-fc-tag-pksq050032","provider":"AFSBio Inc.","version":"1.0","type":"link"}