{"product_id":"recombinant-endostatin-human-bk0337","title":"Recombinant Endostatin, Human - BK0337","description":"Recombinant Endostatin, Human\n\nCatalogue Numbers: BK0337-20, BK0337-100\n\nSizes: 20μg, 100μg\n\nSource: P. pastoris\n\nMolecular Weight: ~20.2 kDa, observed by reducing SDS-PAGE.\n\nPurity: Greater than 97% by SDS-PAGE\n\nBiological Activity: Determined by Endothelial Cell Tube Formation. The cells treated with 10μg\/ml Endostatin showed significant anti-angiogenesis effect.\n\nPhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\n\nFormulation: The sterile filtered solution was lyophilized with 17 mM citric-phosphate buffer, pH 6.2.\n\nAA Sequence: AH SHRDFQPVLH LVALNSPLSG GMRGIRGADF QCFQQARAVG LAGTFRAFLS SRLQDLYSIV RRADRAAVPI VNLKDELLFP SWEALFSGSE GPLKPGARIF SFDGKDVLRH PTWPQKSVWH GSDPNGRRLT ESYCETWRTE APSATGQASS LLGGRLLGQS AASCHHAYIV LCIENSFMTA SK\n\nEndotoxin: Endotoxin level is less than 0.1 ng per μg (1EU\/μg) of Endostatin.\n\nReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\n\nStorage: The lyophilized Endostatin is stable for a few weeks at room temperature, but best stored at -20°C. For the first use, reconstitute in water, aliquot and store at -20°C to avoid multiple freeze-thaws.\n\nUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\n\nDescription: Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues.","brand":"BioWorld","offers":[{"title":"20μg","offer_id":42882264367283,"sku":"BK0337-20","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":42882264400051,"sku":"BK0337-100","price":375.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_63903fee-82b8-41b2-9962-8bffd8e16740.jpg?v=1702050339","url":"https:\/\/afsbio.com\/products\/recombinant-endostatin-human-bk0337","provider":"AFSBio Inc.","version":"1.0","type":"link"}