{"product_id":"recombinant-fgf-10-human","title":"Recombinant FGF-10, Human -","description":"\u003cp\u003eRecombinant FGF-10, Human\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: -10, -50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 19.3 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% as analyzed by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 20 ng\/mL, measured by a cell proliferation assay using 4 MBr-5 cells, corresponding to a specific activity of \u0026gt; 5.0 × 10ˆ4 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: LGQDMVSPEA TNSSSSSFSS PSSAGRHVRS YNHLQGDVRW RKLFSFTKYF\u003cbr\u003e\n LKIEKNGK\u003cbr\u003e\n VS GTKKENCPYS ILEITSVEIG VVAVKAINSN YYLAMNKKGK\u003cbr\u003e\n LYGSKEFNND CKLKERIE\u003cbr\u003e\n EN GYNTYASFNW QHNGRQMYVA LNGKGAPRRG\u003cbr\u003e\n QKTRRKNTSA HFLPMVVHS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant Human FGF-10 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human FGF-10 should be stable up to 1 week at 4°C or up to 3 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in the lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF and receptor binding to FGFR2-IIIb. However, while KGF induces proliferation and differentiation of various epithelial cells, FGF-10 promotes budding and branching morphogenesis during the multi-organ development via mesenchymal-epithelial cell interactions. FGF-10 is critical for lung and limb development, and is regulated by Shh during early development. Recombinant Human FGF-10 produced in E.coli is a single, non-glycosylated polypeptide chain containing 169 amino acids. A fully biologically active molecule, rhFGF-10 has a molecular mass of 19.3 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882234351795,"sku":"-10","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882234384563,"sku":"-50","price":691.77,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_dc243bc0-0ea8-4c09-ba6c-63a814669b8d.jpg?v=1702049785","url":"https:\/\/afsbio.com\/products\/recombinant-fgf-10-human","provider":"AFSBio Inc.","version":"1.0","type":"link"}