{"product_id":"recombinant-fgf-21-mouse","title":"Recombinant FGF-21, Mouse -","description":"\u003cp\u003eRecombinant FGF-21, Mouse\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: -10, -50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 19.9 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 97% as analyzed by SDS-PAGE\u0026amp; HPLC.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 0.5 μg\/ml,measured by a cell proliferation assay using NIH-3T3 cells in the presence of 1.25 µg\/mL mouse Klotho and 10 µg\/mL heparin, corresponding to a specific activity of \u0026gt; 2 × 10ˆ3 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: AYP IPDSSPLLQF GGQVRQRYLY TDDDQDTEAH LEIREDGt VV GAAHRSPESL LELKALKPGV IQILGVKASR FLCQQPDGAL YGSPHFDPEA CSFRELLLED GYNVYQSEAH GLPLRLPQKD SPNQDATSWG PVRFLPMPGL LHEPQDQAGF LPPEPPDVGS SDPLSMVEPL QGRSPSYAS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant Mouse Fibroblast Growth Factor-21(FGF-21), remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Mouse FGF-21 should be stable up to 1 week at 4°C or up to 3 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Fibroblast growth factor-21 (FGF21) belongs to the large FGF family which has at least 23 members. Along with FGF-19\/15 and FGF-23, FGF-21 is categorized as a member of the atypical FGF subfamily, as it must be complexed to the Klotho co-receptor in order to bind to the FGF receptors and activate the downstream signaling pathway. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Recombinant Mouse Fibroblast Growth Factor-21(FGF-21) produced in E.coli is a single non-glycosylated polypeptide chain containing 182 amino acids. A fully biologically active molecule, rmFGF-21 has a molecular mass of 19.9 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882235662515,"sku":"-10","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882235695283,"sku":"-50","price":691.77,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_182d2127-4107-47ae-a691-ad3bd4dd465a.jpg?v=1702049797","url":"https:\/\/afsbio.com\/products\/recombinant-fgf-21-mouse","provider":"AFSBio Inc.","version":"1.0","type":"link"}