{"product_id":"recombinant-flt-3l-his-mouse-bk0202","title":"Recombinant Flt-3L, His, Mouse - BK0202","description":"\u003cp\u003eRecombinant Flt-3L, His, Mouse\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0202-10, BK0202-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: CHO\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 24-30 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% as analyzed by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 10 ng \/ml, measured in a cell proliferation assay using AML5 cells.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: GTPDCYFSHSPISSNFKVKFRELTDHLLKDYPVt VAVNLQDEKHCKALWSLFLAQRWIEQLKt VAGSKMQTLLEDVNTEI\u003cbr\u003e\n HFVTSCTFQPLPECLRFVQTNISHLLKDTCTQLLALKPCIGKACQNFSRCLEVQCQPDSSTLLPPRSPIALEATELPEPR\u003cbr\u003e\n PRHHHHHH\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant murine Flt3L, His remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, murine Flt3L, His should be stable up to 1 week at 4°C or up to 2 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Flt3L, also known as Fms-related tyrosine kinase 3 ligand and SL cytokine, is a single-pass type I membrane protein. It is expressed by stromal cells and T cells. Flt3L signals through tyrosine kinase receptor Flt3\/Flk2 to stimulate the proliferation of early hematopoietic progenitor cells. It synergizes with other growth factors, such as GM-CSF, IL-3 and CSF, to promote the differentiation of both myeloid and lymphoid cells. Alternative splicing and proteolytic cleavage of membrane-bound Flt3L generates a soluble extracellular domain (ECD) isoform with full biological activity.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882250342579,"sku":"BK0202-10","price":256.94,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882250375347,"sku":"BK0202-50","price":813.32,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3e5c51de-d84d-4521-92b6-1fbc9ec0693a.jpg?v=1702050061","url":"https:\/\/afsbio.com\/products\/recombinant-flt-3l-his-mouse-bk0202","provider":"AFSBio Inc.","version":"1.0","type":"link"}