{"product_id":"recombinant-gm-csf-human-p-pastoris-expre-ssed-bk0342","title":"Recombinant GM-CSF, Human (P.pastoris-expressed) - BK0342","description":"\u003cp\u003eRecombinant GM-CSF, Human (P.pastoris-expre Ssed)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0342-10, BK0342-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: P. pastoris\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 26-32 kDa, observed by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as analyzed by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 0.1ng\/ml, measured by proliferation assay of TF-1 cells, corresponding to a specific activity of \u0026gt; 1.0x 10ˆ7 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against 10 mM PB, pH7.0.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MAPARS PSPSTQPWEH VNAIQEARRL LNLSRDTAAE MNEt VEVISE MFDLQEPTCL QTRLELYKQG LRGSLTKLKG PLTMMASHYK QHCPPTPETS CATQIITFES FKENLKDFLL VIPFDCWEPV QE\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt;1.0 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O at 100μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant human Granulocyte Macrophage Colony Stimulating Factor (rhGM-CSF) remains stable up to 12 months at -80°C from date of receipt. Upon reconstitution, rhGM-CSF should be stable up to 4 weeks at 4°C or up to 6 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Human Granulocyte Macrophage Colony Stimulating Factor (hGM-CSF), a hematopoietic growth factor, is mainly involved in granulopoiesis and monocytopoiesis. It is produced by T-cells and macrophages in response to antigens, and by endothelial cells and fibroblasts following induction of variouscytokines [1]. A monomeric protein of 127 amino acidswith six glycosylation sites and two intra disulfide bonds[2,3], glycosylated and non-glycosylated hGM-CSFs show similar biological activities[4]. Other than its connection to the growth and development of granulocytes and macrophages, it is also indispensable for the proliferation of erythroid and megakaryocytic cells[5].Recombinant Human Granulocyte Macrophage Colony Stimulating Factor (rhGM-CSF) produced in P. pastoris a glycosylated polypeptide. A fully biologically active molecule, rhGM-CSF has a molecular mass of 26-32kDa analyzed by SDS-PAGE and is obtained by proprietary refolding and chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882265186483,"sku":"BK0342-10","price":256.94,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882265219251,"sku":"BK0342-50","price":813.32,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e2358a7a-a12a-42ea-8a4d-c96784bc3de1.jpg?v=1702050351","url":"https:\/\/afsbio.com\/products\/recombinant-gm-csf-human-p-pastoris-expre-ssed-bk0342","provider":"AFSBio Inc.","version":"1.0","type":"link"}