{"product_id":"recombinant-gm-csf-mouse-bk0067","title":"Recombinant GM-CSF, Mouse - BK0067","description":"\u003cp\u003eRecombinant GM-CSF, Mouse\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0067-10, BK0067-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 14.3 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 98% as analyzed by SDS-PAGE\u0026amp;HPLC.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 5 pg\/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of \u0026gt;2 x 10ˆ8 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MAPTRSPIt V TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL \u003cbr\u003e\n TCVQTRLKIF E\u003cbr\u003e\n QGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT \u003cbr\u003e\n YADFIDSLKT FLTDIPFECK K\u003cbr\u003e\n PVQK\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant Mouse GM-CSF remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Mouse GM-CSF should be stable up to 1 week at 4°C or up to 3 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine and other immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor that activates effector functions of granulocytes, monocytes\/macrophages and eosinophils.Recombinant Mouse GM-CSF produced in E.coli is a single non-glycosylated polypeptide chain containing 125 amino acids. A fully biologically active molecule, rmGM-CSF has a molecular mass of 14.3 kD analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882240053427,"sku":"BK0067-10","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882240086195,"sku":"BK0067-50","price":691.77,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_9a5a8b69-3f26-4583-b2a0-895e7f7562fa.jpg?v=1702049846","url":"https:\/\/afsbio.com\/products\/recombinant-gm-csf-mouse-bk0067","provider":"AFSBio Inc.","version":"1.0","type":"link"}