{"product_id":"recombinant-human-4-1bb-tnfrsf9-protein-fc-his-tagactive-pksh032027","title":"Recombinant Human 4-1BB\/TNFRSF9 Protein (Fc \u0026 His Tag)(Active) - PKSH032027","description":"\u003cp\u003eRecombinant Human 4-1BB\/TNFRSF9 Protein (Fc \u0026amp; His Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032027-10, PKSH032027-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: 4-1BB; TNFRSF9\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: CD137; ILA; TNFRSF9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cell biology; Cancer; immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q07011\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q07011\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells; but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9\/4-1BBL; and possibly active during T cell activation.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immobilized Human 4-1BBL-His(Cat: PKSH032023) at 0.03μg\/ml(100 μl\/well) can bind Human 4-1BB-Fc. The ED50 of Human 4-1BB-Fc is 7.22 ug\/ml.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Leu24-Gln186\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 44.0 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 55-75 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43118134067379,"sku":"PKSH032027-10","price":172.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43118134100147,"sku":"PKSH032027-50","price":350.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_584385cf-06d9-4209-b68d-1359719e7f1f.png?v=1709636827","url":"https:\/\/afsbio.com\/products\/recombinant-human-4-1bb-tnfrsf9-protein-fc-his-tagactive-pksh032027","provider":"AFSBio Inc.","version":"1.0","type":"link"}