{"product_id":"recombinant-human-adp-ribosyl-cyclase-cyclic-adp-ribose-hydrolase-1-cd38-n-6his-avi-biotinylated-pksh033880","title":"Recombinant Human ADP-ribosyl Cyclase\/cyclic ADP-ribose Hydrolase 1\/CD38 (N-6His-Avi) Biotinylated - PKSH033880","description":"\u003cp\u003eRecombinant Human ADP-ribosyl Cyclase\/cyclic ADP-ribose Hydrolase 1\/CD38 (N-6His-Avi) Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033880-20, PKSH033880-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD38\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: ADP-ribosyl cyclase\/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cancer; immunology; metabolism; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His-Avi\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P28907\u003c\/p\u003e\n\n\u003cp\u003eAccession: P28907\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD38, also known as ADP-ribosyl cyclase\/cyclic ADP-ribose hydrolase 1, is a Signal-anchor for type II membrane protein. CD38 is able to transform NAD+ to ADP-D-ribose and nicotinamide. It also can transform NADP+ to nicotinate-adenine dinucleotide phosphate and nicotinamide. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Val43-Ile300\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 33.3 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 40-50 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43113996452019,"sku":"PKSH033880-20","price":478.8,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43113996484787,"sku":"PKSH033880-100","price":1293.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1a2bd23b-d5dd-4abb-aa40-9da8aceb6775.png?v=1709549948","url":"https:\/\/afsbio.com\/products\/recombinant-human-adp-ribosyl-cyclase-cyclic-adp-ribose-hydrolase-1-cd38-n-6his-avi-biotinylated-pksh033880","provider":"AFSBio Inc.","version":"1.0","type":"link"}