{"product_id":"recombinant-human-akr1c2-protein-pksh032054","title":"Recombinant Human AKR1C2 Protein - PKSH032054","description":"\u003cp\u003eRecombinant Human AKR1C2 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032054-10, PKSH032054-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: AKR1C2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Aldo-Keto Reductase Family 1 Member C2; 3-Alpha-HSD3; Chlordecone Reductase Homolog HAKRD; Dihydrodiol Dehydrogenase 2; DD-2; DD2; Dihydrodiol Dehydrogenase\/Bile Acid-Binding Protein; DD\/BABP; Trans-1; 2-Dihydrobenzene-1; 2-Diol Dehydrogenase; Type III 3-Alpha-Hydroxysteroid Dehydrogenase; AKR1C2; DDH2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P52895\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cancer; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: None\u003c\/p\u003e\n\n\u003cp\u003eAccession: P52895\u003c\/p\u003e\n\n\u003cp\u003eBackground: Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α\/5-β-Steroid Reductases to convert Steroid hormones into the 3-α\/5-α and 3-α\/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Tyr323\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 36.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43083652169907,"sku":"PKSH032054-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43083652202675,"sku":"PKSH032054-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_79ff7a82-cc4c-4a0b-862a-aebf796ca5ba.png?v=1708946254","url":"https:\/\/afsbio.com\/products\/recombinant-human-akr1c2-protein-pksh032054","provider":"AFSBio Inc.","version":"1.0","type":"link"}