{"product_id":"recombinant-human-aldh1a2-protein-his-tag-pksh032053","title":"Recombinant Human ALDH1A2 Protein (His Tag) - PKSH032053","description":"\u003cp\u003eRecombinant Human ALDH1A2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032053-10, PKSH032053-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ALDH1A2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II); Retinal dehydrogenase 2; ALDH1A2; RALDH2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O94788\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience; Developmental Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: O94788\u003c\/p\u003e\n\n\u003cp\u003eBackground: Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate normal and tumor cell growth and differentiation. Several studies showed that ALDH1A2 expression is increased after the appearance of AraC resistance in clinical cases which means this protein is effective in AraC resistance.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Ser518\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mMNaCl, pH7.5, 20% Glycerol.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 58.2 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 50-65 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43083652006067,"sku":"PKSH032053-10","price":368.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43083652038835,"sku":"PKSH032053-50","price":625.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_88967998-2416-4e8c-8d65-bf33a415af04.png?v=1708946251","url":"https:\/\/afsbio.com\/products\/recombinant-human-aldh1a2-protein-his-tag-pksh032053","provider":"AFSBio Inc.","version":"1.0","type":"link"}