{"product_id":"recombinant-human-alk-1-acvrl1-protein-rp00978","title":"Recombinant Human ALK-1\/ACVRL1 Protein - RP00978","description":"\u003cp\u003eRecombinant Human ALK-1\/ACVRL1 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00978-10, RP00978-20, RP00978-50, RP00978-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human ALK-1  Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asp22-Gln118) of human ALK-1  (Accession #NP_000011.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P37023\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 94\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This protein is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine\/threonine kinases.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALK-1 at 4 μg\/mL (100 μL\/well) can bind Human ACVR2B with a linear range of 0.08-2.4 μg\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: DPVKPSRGPLVTCTCESPHCKGPTCRGAWCTVVLVREEGRHPQEHRGCGNLHRELCRGRPTEFVNHYCCDSHLCNHNVSLVLEATQPPSEQPGTDGQ\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198315618483,"sku":"RP00978-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198315651251,"sku":"RP00978-20","price":189.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198315684019,"sku":"RP00978-50","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198315716787,"sku":"RP00978-100","price":336.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_b09de400-0694-42a7-afbf-c7b329e9dc51.png?v=1766960513","url":"https:\/\/afsbio.com\/products\/recombinant-human-alk-1-acvrl1-protein-rp00978","provider":"AFSBio Inc.","version":"1.0","type":"link"}