{"product_id":"recombinant-human-alpha-synuclein-snca-protein-rp01694","title":"Recombinant Human Alpha-synuclein\/SNCA Protein - RP01694","description":"\u003cp\u003eRecombinant Human Alpha-synuclein\/SNCA Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01694-10, RP01694-20, RP01694-50, RP01694-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Alpha-synuclein\/SNCA Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Ala140) of human Alpha-synuclein\/SNCA (Accession #NP_000336.1) fused with no additional amino acid.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: PD1; NACP; PARK1; PARK4; SNCA\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P37840-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 6622\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associated with membranes and the other is disordered, cytosolic form. Synuclein is found predominantly in the presynaptic termini, in both free or membrane-bound forms. SNCA is extensively localized in nucleus of neurons. It has been shown that alpha-Synuclein was highly expressed in the mitochondria in olfactory bulb, hippocampus, striatum, and thalamus, where the cytosolic alpha-Synuclein was also rich.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: NO-tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198263845043,"sku":"RP01694-10","price":140.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198263877811,"sku":"RP01694-20","price":154.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198263910579,"sku":"RP01694-50","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198263943347,"sku":"RP01694-100","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_4f8b57c0-68d2-47bf-a4b5-f831802fbf67.png?v=1766959877","url":"https:\/\/afsbio.com\/products\/recombinant-human-alpha-synuclein-snca-protein-rp01694","provider":"AFSBio Inc.","version":"1.0","type":"link"}