{"product_id":"recombinant-human-angiopoietin-1-ang-1-angpt1277-498-protein-rp01828","title":"Recombinant Human Angiopoietin-1\/ANG-1\/ANGPT1(277-498) Protein - RP01828","description":"\u003cp\u003eRecombinant Human Angiopoietin-1\/ANG-1\/ANGPT1(277-498) Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01828-10, RP01828-20, RP01828-50, RP01828-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Angiopoietin-1\/ANG-1\/ANGPT1(277-498) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Arg277-Phe498) of human Angiopoietin-1\/ANG-1\/ANGPT1 (Accession #NP_001137.2) fused with a 6×His tag at the\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: AGP1; AGPT; ANG1; HAE5; AGPT-1; Angiopoietin-1; ANG-1; ANGPT1\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q15389-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 284\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The angiopoietin (ANGPT)-TIE2\/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist\/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: KREEEKPFRDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSLILHGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFKGPSYSLRSTTMMIRPLDF\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198271086771,"sku":"RP01828-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198271119539,"sku":"RP01828-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198271152307,"sku":"RP01828-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198271185075,"sku":"RP01828-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_e5b994b9-b152-4ef9-9b7b-985182b1cfd5.png?v=1766959956","url":"https:\/\/afsbio.com\/products\/recombinant-human-angiopoietin-1-ang-1-angpt1277-498-protein-rp01828","provider":"AFSBio Inc.","version":"1.0","type":"link"}