{"product_id":"recombinant-human-apoa4-protein-his-tag-pksh033287","title":"Recombinant Human APOA4 Protein (His Tag) - PKSH033287","description":"\u003cp\u003eRecombinant Human APOA4 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033287-10, PKSH033287-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: APOA4\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Apolipoprotein A-IV; Apo-AIV; ApoA-IV; Apolipoprotein A4; APOA4\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; Cardiovascular; Cancer; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P06727\u003c\/p\u003e\n\n\u003cp\u003eAccession: P06727\u003c\/p\u003e\n\n\u003cp\u003eBackground: Apolipoprotein A4 (APOA4) is a secreted protein that belongs to the apolipoprotein A1\/A4\/E family. Apoa-IV is a major component of HDL and chylomicrons. APOA4 is secreted into circulation on the surface of newly synthesized chylomicron particles. APOA4 play a role in the regulation of appetite and satiety in rodent models. APOA4 involved in chylomicrons and VLDL secretion and catabolism and required for efficient activation of lipoprotein lipase by ApoC-II. In addition, APOA4 is a potent activator of lecithin-cholesterol acyltransferase in vitro.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Glu21-Ser396\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 44.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 46 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113942974643,"sku":"PKSH033287-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113943007411,"sku":"PKSH033287-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_eb58f1ce-889b-4854-b9ad-28738378c7a1.png?v=1709549001","url":"https:\/\/afsbio.com\/products\/recombinant-human-apoa4-protein-his-tag-pksh033287","provider":"AFSBio Inc.","version":"1.0","type":"link"}