{"product_id":"recombinant-human-apolipoproteina-iv-apoa4-protein-rp01854","title":"Recombinant Human ApolipoproteinA-IV\/APOA4 Protein - RP01854","description":"\u003cp\u003eRecombinant Human ApolipoproteinA-IV\/APOA4 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01854-10, RP01854-20, RP01854-50, RP01854-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Apolipoprotein A-IV\/APOA4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu21-Ser396) ofHuman Apolipoprotein A-IV\/APOA4 (Accession #NP_000473.2) fused with a His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: APOA4, Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4.\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P06727\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 337\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90% as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Apolipoprotein A-IV (ApoA-IV), first discovered in rat plasma in the 1970s , is a 46 kD glycoprotein with relatively high concentrations in plasma (15–37 mg\/dL). It is expressed predominantly in the mammalian small intestine (with highest expression in the duodenum), and also expressed in rodent liver at lower levels. Sensing lipid absorption in enterocytes , ApoA-IV is synthesized and packaged with lipids and other apolipoproteins into chylomicrons and secreted through the lymphatic system into the blood. Once there, as a member of exchangeable apolipoproteins, ApoA-IV dissociates from chylomicrons and transfers to HDL (high density lipoprotein) particles or circulates in lipid-free form.ApoA-IV may protect against atherosclerosis , mediate reverse cholesterol transport , act as an anti-inflammatory agent and modulate intestinal lipid absorption.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: EVSADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEVNTYAGDLQKKLVPFATELHERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVSTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLPELEQQQEQQQEQQQEQVQMLAPLES\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198269120691,"sku":"RP01854-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198269153459,"sku":"RP01854-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198269186227,"sku":"RP01854-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198269218995,"sku":"RP01854-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_3214b28a-a40b-4ec3-b59e-ab498a70fba9.png?v=1766959935","url":"https:\/\/afsbio.com\/products\/recombinant-human-apolipoproteina-iv-apoa4-protein-rp01854","provider":"AFSBio Inc.","version":"1.0","type":"link"}