{"product_id":"recombinant-human-arginase-1-arg1-protein-e-coli-his-tagactive-pksh032091","title":"Recombinant Human Arginase-1\/ARG1 Protein (E.coli, His Tag)(Active) - PKSH032091","description":"\u003cp\u003eRecombinant Human Arginase-1\/ARG1 Protein (E.coli, His Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032091-10, PKSH032091-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Arginase-1; ARG1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Arginase-1; Liver-type arginase; Type I arginase; ARG1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eApplication: Enzyme\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P05089\u003c\/p\u003e\n\n\u003cp\u003eAccession: P05089\u003c\/p\u003e\n\n\u003cp\u003eBackground: ARG1 is a member of the ureohydrolase family of enzymes. ARG1 can catalyze the hydrolysis of arginine to ornithine and urea. In the urea cycle, ARG1 catalyzes the fifth and final step, a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. ARG1 is a cytosolic enzyme and expressed widely in the liver as part of the urea cycle. Inherited deficiency of this ARG1 causes argininemia, which is an autosomal recessive disorder characterized by hyperammonemia.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Measured by the production of urea during the hydrolysis of arginine. The specific activity is 6136. 25 pmol\/min\/µg.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-lys322\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, 20% Glycerol, 1mM DTT, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 35.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 40 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43118134395059,"sku":"PKSH032091-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43118134427827,"sku":"PKSH032091-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b7c5cad4-5b4a-4b45-bad8-1a00de7438a8.png?v=1709636834","url":"https:\/\/afsbio.com\/products\/recombinant-human-arginase-1-arg1-protein-e-coli-his-tagactive-pksh032091","provider":"AFSBio Inc.","version":"1.0","type":"link"}