{"product_id":"recombinant-human-arylsulfatase-a-arsa-protein-his-tag-pksh032093","title":"Recombinant Human Arylsulfatase A\/ARSA Protein (His Tag) - PKSH032093","description":"\u003cp\u003eRecombinant Human Arylsulfatase A\/ARSA Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032093-10, PKSH032093-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Arylsulfatase A; ARSA\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Arylsulfatase A; ASA; Cerebroside-Sulfatase; ARSA\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P15289\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Tags \u0026amp; Cell Markers; Cell biology; Neuroscience; Cancer; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P15289\u003c\/p\u003e\n\n\u003cp\u003eBackground: Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Arg19-Ala507\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 52.9 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 55 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43083655807155,"sku":"PKSH032093-10","price":404.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43083655839923,"sku":"PKSH032093-50","price":792.4,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_0c683ba3-b0e9-4c8f-88f6-6d7ce33aa568.png?v=1708946351","url":"https:\/\/afsbio.com\/products\/recombinant-human-arylsulfatase-a-arsa-protein-his-tag-pksh032093","provider":"AFSBio Inc.","version":"1.0","type":"link"}