{"product_id":"recombinant-human-atxn7l1-protein-his-tag-pdeh100313","title":"Recombinant Human ATXN7L1 protein (His tag) - PDEH100313","description":"\u003cp\u003eRecombinant Human ATXN7L1 protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PDEH100313-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ATXN7L1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Ataxin-7-like protein 1; ATXN7L1; Ataxin-7-like protein 1; Ataxin-7-like protein 4\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His \u0026amp; C-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9ULK2\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9ULK2-2\u003c\/p\u003e\n\n\u003cp\u003eBackground: ATXN7 is found in the cytoplasm of all the populations of neurons analyzed in control brains, but nuclear labeling is observed in some neurons with a frequency and intensity weakly correlated with the topography of lesions in patients. Ataxin-7 is a component of the Tata binding protein (TBP)-free TAF-containing complex (TFTC) and the SPT3\/TAF9\/GCN5 acetyltransferase complex (STAGA), which is implicated in several steps of transcriptional regulation such as histone acetylation\/deubiquitinylation and recruitment of the preinitiation complex to promoters.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1- Ala 146\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 15.95 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 20 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104343457971,"sku":"PDEH100313-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b79e74b4-54fc-4511-a845-b90575f88c77.png?v=1709294763","url":"https:\/\/afsbio.com\/products\/recombinant-human-atxn7l1-protein-his-tag-pdeh100313","provider":"AFSBio Inc.","version":"1.0","type":"link"}