{"product_id":"recombinant-human-b7-1-cd80-protein-rp00065","title":"Recombinant Human B7-1\/CD80 Protein - RP00065","description":"\u003cp\u003eRecombinant Human B7-1\/CD80 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00065-10, RP00065-20, RP00065-50, RP00065-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human B7-1\/CD80 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Val35-Asn242) of human B7-1\/CD80 (Accession #NP_005182.1) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7, CD80\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P33681\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 941\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant human CD80 at 2 μg\/mL (100 μL\/well) can bind Recombinant human CTLA-4 with a linear range of 10-50 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: VIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDN\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198295335091,"sku":"RP00065-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198295367859,"sku":"RP00065-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198295400627,"sku":"RP00065-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198295433395,"sku":"RP00065-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_faae7c1e-d207-4556-98f7-b862bad95356.png?v=1766960253","url":"https:\/\/afsbio.com\/products\/recombinant-human-b7-1-cd80-protein-rp00065","provider":"AFSBio Inc.","version":"1.0","type":"link"}