{"product_id":"recombinant-human-bcas2-dam1-protein-his-t7-tag-pksh032111","title":"Recombinant Human BCAS2\/DAM1 Protein (His \u0026 T7 Tag) - PKSH032111","description":"\u003cp\u003eRecombinant Human BCAS2\/DAM1 Protein (His \u0026amp; T7 Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032111-10, PKSH032111-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BCAS2; DAM1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Pre-mRNA-Splicing Factor SPF27; Breast Carcinoma-Amplified Sequence 2; DNA Amplified in Mammary Carcinoma 1 Protein; Spliceosome-Associated Protein SPF 27; BCAS2; DAM1\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O75934\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Tags \u0026amp; Cell Markers; epigenetics and nuclear signal\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His \u0026amp; N-T7\u003c\/p\u003e\n\n\u003cp\u003eAccession: O75934\u003c\/p\u003e\n\n\u003cp\u003eBackground: Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala2-Phe225\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 2mM DTT, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43083657117875,"sku":"PKSH032111-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43083657150643,"sku":"PKSH032111-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b63b555e-122c-4323-9803-de7e5639d082.png?v=1708946388","url":"https:\/\/afsbio.com\/products\/recombinant-human-bcas2-dam1-protein-his-t7-tag-pksh032111","provider":"AFSBio Inc.","version":"1.0","type":"link"}