{"product_id":"recombinant-human-bcl6-b-cell-cll-lymphoma-6-protein-aa-1-150-his-trx-tag-pksh030910","title":"Recombinant Human BCL6\/B-cell CLL lymphoma 6 Protein (aa 1-150, His \u0026 Trx Tag) - PKSH030910","description":"Recombinant Human BCL6\/B-cell CLL lymphoma 6 Protein (aa 1-150, His \u0026amp; Trx Tag)\n\nSize: 100μg\n\nCatalogue Numbers: PKSH030910-100\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: BCL6\n\nTarget Synonym: BCL5; BCL6A; LAZ3; ZBTB27; ZNF51\n\nUNIProt ID: P41182\n\nResearch Areas: Cancer; epigenetics and nuclear signal\n\nTarget Species: Human\n\nExpression Host: E.coli\n\nFusion Tag: N-Trx-His\n\nAccession: P41182\n\nBackground: The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’ s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon specific DNA-binding and the presence of an intact N-terminal half of the protein.\n\nSequence: Met 1-Met 150\n\nPurity: \u0026gt; 92 % as determined by reducing SDS-PAGE.\n\nFormulation: Lyophilized from sterile 20mM Tris, 10% glycerol, pH 8.0\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\nPlease refer to the specific buffer information in the printed manual.\n\nReconstitution: Please refer to the printed manual for detailed information.\n\nEndotoxin: Please contact us for more information.\n\nCalculated MW: 34.2 kDa\n\nObserved MW: 33 kDa\n\nStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\n\nShipping: This product is provided as lyophilized powder which is shipped with ice packs.\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43083644862643,"sku":"PKSH030910-100","price":680.4,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_19819c89-587c-4e7e-8ce7-e7879dd07b88.png?v=1708946012","url":"https:\/\/afsbio.com\/products\/recombinant-human-bcl6-b-cell-cll-lymphoma-6-protein-aa-1-150-his-trx-tag-pksh030910","provider":"AFSBio Inc.","version":"1.0","type":"link"}