{"product_id":"recombinant-human-bcma-tnfrsf17-c-fc-avi-biotinylated-pksh033857","title":"Recombinant Human BCMA\/TNFRSF17 (C-Fc-Avi) Biotinylated - PKSH033857","description":"\u003cp\u003eRecombinant Human BCMA\/TNFRSF17 (C-Fc-Avi) Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033857-20, PKSH033857-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BCMA; TNFRSF17\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Tumor necrosis factor receptor superfamily member 17; TNFRSF17; B-cell maturation protein; CD269\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; Cancer; immunology;\u003c\/p\u003e \n\n\u003cp\u003eConjugation: Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc-Avi\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q02223\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q02223\u003c\/p\u003e\n\n\u003cp\u003eBackground: B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met1-Ala54\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 34.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 38-45 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43113994485939,"sku":"PKSH033857-20","price":478.8,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43113994518707,"sku":"PKSH033857-100","price":1293.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_bce9423a-22af-4f69-a4b7-24b6e35479f6.png?v=1709549905","url":"https:\/\/afsbio.com\/products\/recombinant-human-bcma-tnfrsf17-c-fc-avi-biotinylated-pksh033857","provider":"AFSBio Inc.","version":"1.0","type":"link"}