{"product_id":"recombinant-human-beta-2-microglobulin-b2m-protein-rp00105","title":"Recombinant Human Beta-2-microglobulin\/B2M Protein - RP00105","description":"\u003cp\u003eRecombinant Human Beta-2-microglobulin\/B2M Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00105-10, RP00105-20, RP00105-50, RP00105-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Beta-2-microglobulin\/B2M Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ile21-Met119) of human B2M\/Beta-2-microglobulin (Accession #NP_004039.1) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: B2M, IMD43, beta-2-microglobulin, IMD43\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P61769\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 567\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This protein is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human B2M at 2 μg\/mL (100 μL\/well) can bind Recombinant Human CD8 alpha with a linear range of 31.25-341 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198299693235,"sku":"RP00105-10","price":182.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198299726003,"sku":"RP00105-20","price":217.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198299758771,"sku":"RP00105-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198299791539,"sku":"RP00105-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_a049b7a7-1e28-402b-80fb-39127c3e4494.png?v=1766960308","url":"https:\/\/afsbio.com\/products\/recombinant-human-beta-2-microglobulin-b2m-protein-rp00105","provider":"AFSBio Inc.","version":"1.0","type":"link"}