{"product_id":"recombinant-human-blvra-protein-his-tag-pksh032118","title":"Recombinant Human BLVRA Protein (His Tag) - PKSH032118","description":"\u003cp\u003eRecombinant Human BLVRA Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032118-10, PKSH032118-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BLVRA\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BLVRA; Biliverdin reductase A; BVR A; Biliverdin-IX alpha-reductase; BLVR; BVR\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P53004\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cell biology; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P53004\u003c\/p\u003e\n\n\u003cp\u003eBackground: Human Biliverdin reductase A (BLVRA) is belonged to the Gfo\/Idh\/MocA family and Biliverdin reductase subfamily. BLVRA is an enzyme that in humans is encoded by the BLVRA gene. BLVRA plays an important role in reducing the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. BLVRA acts on biliverdin by reducing its double-bond between the pyrrole rings into a single-bond. It accomplishes this using NADPH + H+ as an electron donor, forming bilirubin and NADP+ as products.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Glu6-Ser294\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, 0.05% Brij35, 20%Glycerol, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 33.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 40 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43083657543859,"sku":"PKSH032118-10","price":385.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43083657576627,"sku":"PKSH032118-50","price":735.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5a19b299-9894-4098-955b-de260b8c9095.png?v=1708946402","url":"https:\/\/afsbio.com\/products\/recombinant-human-blvra-protein-his-tag-pksh032118","provider":"AFSBio Inc.","version":"1.0","type":"link"}