{"product_id":"recombinant-human-bmpr-1b-alk-6-cdw293-protein-rp01222","title":"Recombinant Human BMPR-1B\/ALK-6\/CDw293 Protein - RP01222","description":"\u003cp\u003eRecombinant Human BMPR-1B\/ALK-6\/CDw293 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01222-10, RP01222-20, RP01222-50, RP01222-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Active Recombinant Human BMPR-1B\/ALK-6 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys14-Arg126) of human BMPR-IB\/ALK-6 (Accession #NP_001194.1) fused with a Fc, 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ALK-6, ALK6, AMDD, BDA1D, BDA2, CDw293, BMPR1B, ALK-6, ALK6, AMDD, BDA1D, BDA2, CDw293, bone morphogenetic protein receptor type-1B\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O00238\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 658\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: 1.Measured by its binding ability in a functional ELISA. Immobilized Human BMP2 at 4 μg\/mL (100 μL\/well) can bind Human BMPRIB with a linear range of 20-338 ng\/mL.|2.Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells.The ED50 for this effect is 0.6-2.3 μg\/mL in the presence of 30 ng\/mL of rhBMP-4.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFc\u0026amp;His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: KKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198287306931,"sku":"RP01222-10","price":182.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198287339699,"sku":"RP01222-20","price":217.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198287372467,"sku":"RP01222-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198287405235,"sku":"RP01222-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_998115eb-aa16-466c-b499-172823f14e03.png?v=1766960155","url":"https:\/\/afsbio.com\/products\/recombinant-human-bmpr-1b-alk-6-cdw293-protein-rp01222","provider":"AFSBio Inc.","version":"1.0","type":"link"}