{"product_id":"recombinant-human-bpi-cap57-protein-his-tag-pksh032108","title":"Recombinant Human BPI\/CAP57 Protein (His Tag) - PKSH032108","description":"\u003cp\u003eRecombinant Human BPI\/CAP57 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032108-10, PKSH032108-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BPI; CAP57\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Bactericidal permeability-increasing protein; BPI; CAP57\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P17213\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Microbiology; Cardiovascular; immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P17213\u003c\/p\u003e\n\n\u003cp\u003eBackground: Bactericidal permeability-increasing protein(BPI for short), is a secreted protein which belongs to the BPI\/LBP\/Plunc superfamily, BPI\/LBP family. It exists as a monomer or a disulfide-linked homodimer. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria. This specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. BPI has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, and this activity is inhibited by LPS from P.aeruginosa.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Val32-Lys487\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 52.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 50 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43083656822963,"sku":"PKSH032108-10","price":163.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43083656855731,"sku":"PKSH032108-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_edb5a669-d563-45f9-806f-5ab9cd61d1cb.png?v=1708946380","url":"https:\/\/afsbio.com\/products\/recombinant-human-bpi-cap57-protein-his-tag-pksh032108","provider":"AFSBio Inc.","version":"1.0","type":"link"}