{"product_id":"recombinant-human-brain-natriuretic-peptide-bnp-protein-his-flag-tag-pksh032127","title":"Recombinant Human Brain Natriuretic Peptide\/BNP Protein (His \u0026 Flag Tag) - PKSH032127","description":"\u003cp\u003eRecombinant Human Brain Natriuretic Peptide\/BNP Protein (His \u0026amp; Flag Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032127-10, PKSH032127-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Brain Natriuretic Peptide; BNP\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Natriuretic peptides B; Gamma-brain natriuretic peptide; NPPB; BNP\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P16860\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cardiovascular; Neuroscience;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His-Flag\u003c\/p\u003e\n\n\u003cp\u003eAccession: P16860\u003c\/p\u003e\n\n\u003cp\u003eBackground: Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12 kDa BNP precursor gives rise to N-terminal Pro BNP (NT-proBNP) and mature BNP. N-terminal proB-type natriuretic peptide (NT-proBNP); a useful marker of heart failure (HF); is considered to be secreted mainly from the ventricle; increased serum NT-proBNP levels are also encountered in conditions such as atrial fibrillation (AF) and atrial septal defect in patients without HF.\u003c\/p\u003e\n\n\u003cp\u003eSequence: His27-Arg102\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 11.0 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 14 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43092724678835,"sku":"PKSH032127-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43092724711603,"sku":"PKSH032127-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_18f80b94-150a-4c2b-9b82-5b3d6d7624ea.png?v=1709119077","url":"https:\/\/afsbio.com\/products\/recombinant-human-brain-natriuretic-peptide-bnp-protein-his-flag-tag-pksh032127","provider":"AFSBio Inc.","version":"1.0","type":"link"}