{"product_id":"recombinant-human-butyrophilin-3a2-btn3a2-protein-his-tag-pksh032133","title":"Recombinant Human Butyrophilin 3A2\/BTN3A2 Protein (His Tag) - PKSH032133","description":"\u003cp\u003eRecombinant Human Butyrophilin 3A2\/BTN3A2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032133-10, PKSH032133-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Butyrophilin 3A2; BTN3A2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Butyrophilin subfamily 3 member A2; BT3.2; BTF3; BTF4; BTN3A2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P78410\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P78410\u003c\/p\u003e\n\n\u003cp\u003eBackground: Butyrophilin subfamily 3 member A2, also known as BT3.2, BTF3, BTF4 and BTN3A2, is a single-pass type I membrane protein. It is a member of the butyrophilin (BTN) family and the immunoglobulin (IG) superfamily. Mature human BTN3A2 is a 305 amino acid (aa) glycoprotein. It contains a 219 aa extracellular region with one V-type Ig-like domain, and a 65 aa cytoplasmic tail. The cytoplasmic region undergoes phosphorylation on two serines. There are three potential splice forms. BTN3A2 is postulated to be expressed on immune-related cells, as it has a structural similarity to MHC and CD80\/CD86 molecules. It plays a role in T-cell responses in the adaptive immune response and inhibits the release of IFNG from activated T-cells.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gln30-Trp248\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 24.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 29 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43092725956787,"sku":"PKSH032133-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43092725989555,"sku":"PKSH032133-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8d2c861a-6a98-4fbc-99bf-cacc2b9ef200.png?v=1709119093","url":"https:\/\/afsbio.com\/products\/recombinant-human-butyrophilin-3a2-btn3a2-protein-his-tag-pksh032133","provider":"AFSBio Inc.","version":"1.0","type":"link"}