{"product_id":"recombinant-human-butyrophilin-subfamily-1-member-a1-btn1a1-c-fc-pksh033945","title":"Recombinant Human Butyrophilin Subfamily 1 Member A1\/BTN1A1 (C-Fc) - PKSH033945","description":"\u003cp\u003eRecombinant Human Butyrophilin Subfamily 1 Member A1\/BTN1A1 (C-Fc)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033945-10, PKSH033945-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BTN1A1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Butyrophilin Subfamily 1 Member A1; BT; BTN1A1; BTN\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q13410\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q13410\u003c\/p\u003e\n\n\u003cp\u003eBackground: Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala27-Arg242\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 50.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60-80 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43114002514099,"sku":"PKSH033945-10","price":140.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43114002579635,"sku":"PKSH033945-50","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_51fa1b7c-c6d2-4f9b-9fd2-f0e6534a25cf.png?v=1709550074","url":"https:\/\/afsbio.com\/products\/recombinant-human-butyrophilin-subfamily-1-member-a1-btn1a1-c-fc-pksh033945","provider":"AFSBio Inc.","version":"1.0","type":"link"}