{"product_id":"recombinant-human-butyrophilin-subfamily-3-member-a1-btn3a1-c-fc-avi-biotinylated-pksh034003","title":"Recombinant Human Butyrophilin Subfamily 3 Member A1\/BTN3A1 (C-Fc-Avi) Biotinylated - PKSH034003","description":"\u003cp\u003eRecombinant Human Butyrophilin Subfamily 3 Member A1\/BTN3A1 (C-Fc-Avi) Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH034003-20, PKSH034003-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BTN3A1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Butyrophilin subfamily 3 member A1; CD277; BTN3A1; BTF5\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc-Avi\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O00481\u003c\/p\u003e\n\n\u003cp\u003eAccession: O00481\u003c\/p\u003e\n\n\u003cp\u003eBackground: Butyrophilin Subfamily 3 Member A1 (BTN3A1\/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gln30-Gly254\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 52.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 58-62 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43114009821363,"sku":"PKSH034003-20","price":478.8,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43114009854131,"sku":"PKSH034003-100","price":1293.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9d1e2ecd-1641-498d-8a67-7aeaab3429ed.png?v=1709550169","url":"https:\/\/afsbio.com\/products\/recombinant-human-butyrophilin-subfamily-3-member-a1-btn3a1-c-fc-avi-biotinylated-pksh034003","provider":"AFSBio Inc.","version":"1.0","type":"link"}