{"product_id":"recombinant-human-cadherin-11-cdh11-protein-his-tag-pksh032136","title":"Recombinant Human Cadherin-11\/CDH11 Protein (His Tag) - PKSH032136","description":"\u003cp\u003eRecombinant Human Cadherin-11\/CDH11 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032136-10, PKSH032136-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Cadherin-11; CDH11\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Cadherin 11 Type 2 OB-cadherin (Osteoblast); Cadherin 11 Type 2 OB-Cadherin (Osteoblast) Isoform CRA_c; CDH11\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q96CZ9\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q96CZ9\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells; and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in the brain. Mature cadherin proteins consists of a large N-terminal extracellular domain; a single membrane-spanning domain; and a small highly conserved C-terminal cytoplasmic domain. It is shown that Cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Phe23-Thr617\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 66.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 82 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43149111197875,"sku":"PKSH032136-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43149111230643,"sku":"PKSH032136-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_149c728a-6bc6-470f-81c9-2ee168b3a483.png?v=1710340833","url":"https:\/\/afsbio.com\/products\/recombinant-human-cadherin-11-cdh11-protein-his-tag-pksh032136","provider":"AFSBio Inc.","version":"1.0","type":"link"}