{"product_id":"recombinant-human-calcineurin-b-cnb-protein-his-tag-pksh032144","title":"Recombinant Human Calcineurin B\/CNB Protein (His Tag) - PKSH032144","description":"\u003cp\u003eRecombinant Human Calcineurin B\/CNB Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032144-10, PKSH032144-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Calcineurin B; CNB\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Calcineurin Subunit B Type 1; Protein Phosphatase 2B Regulatory Subunit 1; Protein Phosphatase 3 Regulatory Subunit B Alpha Osoform 1; PPP3R1; CNA2; CNB\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P63098\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; immunology;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P63098\u003c\/p\u003e\n\n\u003cp\u003eBackground: Calcineurin Subunit B Type 1 belongs to the calcineurin regulatory subunit family. Calcineurin Subunit B Type 1 is a Ser\/Thr-specific calcium and calmodulin-dependent protein phosphatase. It is composed of a catalytic subunit (A) and a regulatory subunit (B). It contains four EF-hand domains and four functional calcium-binding sites. Calcineurin Subunit B Type 1 plays an improtant role in the T cell activation pathway.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Val170\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 2mM DTT, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 21.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 18 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43092727562419,"sku":"PKSH032144-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43092727595187,"sku":"PKSH032144-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_539b1b11-0124-4b96-9622-a176b235429e.png?v=1709119118","url":"https:\/\/afsbio.com\/products\/recombinant-human-calcineurin-b-cnb-protein-his-tag-pksh032144","provider":"AFSBio Inc.","version":"1.0","type":"link"}