{"product_id":"recombinant-human-camk4-camkiv-protein-gst-tag-pksh031495","title":"Recombinant Human CAMK4\/CaMKIV Protein (GST Tag) - PKSH031495","description":"\u003cp\u003eRecombinant Human CAMK4\/CaMKIV Protein (GST Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH031495-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CAMK4, CaMKIV\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: caMK, CaMK-GR, CaMKIV, IV\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Neuroscience, epigenetics and nuclear signal,\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: Baculovirus-Insect Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-GST\u003c\/p\u003e\n\n\u003cp\u003eAccession: NP_001735.1\u003c\/p\u003e\n\n\u003cp\u003eBackground: Ca2+\/ calmodulin-dependent protein kinase 4 (CAMKⅣ) belongs to the serine\/threonine protein kinase family, and to the Ca2+\/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme implicated in the phophoinositide amplification cascade. Ca2+\/calmodulin dependent protein kinase (CAMK) can be activated by the introcellular increased Ca2+ and then apt to combine with the target protein. Ca2+\/ calmodulin-dependent protein kinase 4 (CAMKⅣ) is a multifunctional CaM-dependent kinase protein with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. All of the isforms of this family, including myosin light chain kinase, phosphorylase kinase, CaMK1, CaMKⅢ and CaMKⅣ have EF-hand structure.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Tyr 473\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 82 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile 50mM Tris, 100mM NaCl, 0.5mM PMSF, pH 8.0\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 79 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 100 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μg","offer_id":43155037454515,"sku":"PKSH031495-50","price":680.4,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3d4a6e70-1e25-4a35-8d72-26797e4f0e06.png?v=1710437191","url":"https:\/\/afsbio.com\/products\/recombinant-human-camk4-camkiv-protein-gst-tag-pksh031495","provider":"AFSBio Inc.","version":"1.0","type":"link"}