{"product_id":"recombinant-human-carbonic-anhydrase-1-ca1-protein-his-tagactive-pksh032156","title":"Recombinant Human Carbonic Anhydrase 1\/CA1 Protein (His Tag)(Active) - PKSH032156","description":"\u003cp\u003eRecombinant Human Carbonic Anhydrase 1\/CA1 Protein (His Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032156-10, PKSH032156-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Carbonic Anhydrase 1; CA1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Carbonic Anhydrase 1; Carbonate Dehydratase I; Carbonic Anhydrase B; CAB; Carbonic Anhydrase I; CA-I; CA1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cell biology; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eApplication: Enzyme\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P00915\u003c\/p\u003e\n\n\u003cp\u003eAccession: P00915\u003c\/p\u003e\n\n\u003cp\u003eBackground: Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonamide derivatives and coumarins. In addition, CA1 is a zinc metalloenzyme that has reversible hydration of carbon dioxide. It can hydrate cyanamide to urea.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Measured by its esterase activity. The specific activity is 78.1 pmol\/min\/µg.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala2-Phe261\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 29.9 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 30 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43118134624435,"sku":"PKSH032156-10","price":309.4,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43118134657203,"sku":"PKSH032156-50","price":509.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_dec8c7aa-70b2-439c-ab2e-94742cf874a6.png?v=1709636841","url":"https:\/\/afsbio.com\/products\/recombinant-human-carbonic-anhydrase-1-ca1-protein-his-tagactive-pksh032156","provider":"AFSBio Inc.","version":"1.0","type":"link"}