{"product_id":"recombinant-human-carbonic-anhydrase-2-protein-rp00034","title":"Recombinant Human Carbonic anhydrase 2 Protein - RP00034","description":"\u003cp\u003eRecombinant Human Carbonic anhydrase 2 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00034-10, RP00034-20, RP00034-50, RP00034-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Carbonic anhydrase 2 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ser2-Lys260) of human Carbonic anhydrase II (Accession #NP_000058.1).\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CA2, CA-II, CAC, CAII, Car2, HEL-76, HEL-S-282, carbonic anhydrase 2, CA-II, CAC, CAII, Car2, HEL-76, HEL-S-282\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P00918\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 760\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. CA2 is a cytosolic enzyme with the highest activity among all known CAs. Mutations in the CA2 gene result in the CA II deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its esterase activity. The specific activity is \u0026gt;840 pmoles\/min\/μg, as measured with 1 mM 4-Nitrophenyl acetate and 0.1 μg enzyme at 400 nm in 100 μL of 12.5 mM Tris, 75 mM NaCl, pH 7.5.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198291370163,"sku":"RP00034-10","price":182.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198291402931,"sku":"RP00034-20","price":217.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198291435699,"sku":"RP00034-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198291468467,"sku":"RP00034-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_3be5661b-c99f-4de1-a16c-f21ae0c76f23.png?v=1766960204","url":"https:\/\/afsbio.com\/products\/recombinant-human-carbonic-anhydrase-2-protein-rp00034","provider":"AFSBio Inc.","version":"1.0","type":"link"}