{"product_id":"recombinant-human-ccl1-i-309-protein-pksh033809","title":"Recombinant Human CCL1\/I-309 Protein - PKSH033809","description":"\u003cp\u003eRecombinant Human CCL1\/I-309 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033809-10, PKSH033809-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CCL1; I-309\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-Secreted Protein I-309; \u003cbr\u003e\nCCL1; SCYA1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: None\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P22362\u003c\/p\u003e\n\n\u003cp\u003eAccession: P22362\u003c\/p\u003e\n\n\u003cp\u003eBackground: Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a\u003cbr\u003e\ncentral role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a\u003cbr\u003e\nhomologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence\u003cbr\u003e\nidentity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines.\u003cbr\u003e\nCCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface\u003cbr\u003e\nchemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell\u003cbr\u003e\nfusion and virus infection.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Lys24-Lys96\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 8.62 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 10 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113993470131,"sku":"PKSH033809-10","price":341.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113993502899,"sku":"PKSH033809-50","price":932.4,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_0cff54a1-ca29-4c1c-aec2-066b1cb9fb36.png?v=1709549882","url":"https:\/\/afsbio.com\/products\/recombinant-human-ccl1-i-309-protein-pksh033809","provider":"AFSBio Inc.","version":"1.0","type":"link"}