{"product_id":"recombinant-human-ccl5-rantes-protein-rp01750lq","title":"Recombinant Human CCL5\/RANTES Protein - RP01750LQ","description":"\u003cp\u003eRecombinant Human CCL5\/RANTES Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01750LQ-10, RP01750LQ-20, RP01750LQ-50, RP01750LQ-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human CCL5\/RANTES Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ser24-Ser91) of human CCL5\/RANTES (Accession #NP_002976.2) fused with and a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P13501\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 6352\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CCL5 (Catalog: RP01750LQ) at 5 μg\/mL (100 μL\/well) can bind Mouse CXCL4 (Catalog: RP03170) with a linear range of 10-252.6 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.22 μm filtered solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: SPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198332461235,"sku":"RP01750LQ-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198332494003,"sku":"RP01750LQ-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198332526771,"sku":"RP01750LQ-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198332559539,"sku":"RP01750LQ-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_0fcdde77-3a2a-44b8-9e11-be371b139679.png?v=1766960694","url":"https:\/\/afsbio.com\/products\/recombinant-human-ccl5-rantes-protein-rp01750lq","provider":"AFSBio Inc.","version":"1.0","type":"link"}