{"product_id":"recombinant-human-cd155-pvr-necl5-protein-his-tag-pdmh100147","title":"Recombinant Human CD155\/PVR\/NECL5 protein (His tag) - PDMH100147","description":"\u003cp\u003eRecombinant Human CD155\/PVR\/NECL5 protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDMH100147-20, PDMH100147-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD155; PVR; NECL5\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P15151\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Microbiology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P15151\u003c\/p\u003e\n\n\u003cp\u003eBackground: Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV); an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains; a transmembrane segment; and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α; β; γ; and δ) with identical extracellular domains.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met1-Asn343\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 37.62 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43083628576947,"sku":"PDMH100147-20","price":264.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43083628609715,"sku":"PDMH100147-100","price":418.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_64429bbd-c73b-4d37-a10b-28d294444274.png?v=1708945584","url":"https:\/\/afsbio.com\/products\/recombinant-human-cd155-pvr-necl5-protein-his-tag-pdmh100147","provider":"AFSBio Inc.","version":"1.0","type":"link"}